Text-11 snps and neighboring sequences role in causing male infertility in some ethnic groups of Iranian and their potential role in estimating divergence time

X-chromosome and its independent loci recently gained importance in genetic investigations concerned with disease control-case studies, population analyses, phylogenetic investigations. Infertility lack of normal reproduction are important issues health. Aazoospermia is a kind infertility men whose semen contains no sperm can affect about 1-20% the male population. The majority cases spermatogenic failure humans idiopathic, underlying causes postulated to be genetic. We analyze potential association between seven X-Chromosome SNPs neighboring sequences azoospermia four ethnic populations Iran. also carried out analyses produce data on variability, structure, gene flow, time divergence these groups, for first time. As genes/SNPs homozygous condition, study we used multivariate statistical methods, which revealed role variable sites close studied infertility. Haplotype groups were identified each SNPs. results showed flow among due migration inter-breeding Bayesian analysis sequence suggested 2-30 KY.